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Toluca vs Santos Laguna Prediction - 21 September 2026

Liga MXMexicoFull time
Toluca
2-3
Santos Laguna

Our pick:Home win

74%Odds 1.30Lost

Correct score2-0Alternative3-0

Bookmaker odds

Home1.20price falling, opened at 1.26
Draw6.55price rising, opened at 5.65
Away10.50price rising, opened at 9.15
More markets
Total goals
Over 1.51.04price falling, opened at 1.05
Under 1.56.80price rising, opened at 6.30
Over 2.51.27price falling, opened at 1.31
Under 2.53.14price rising, opened at 2.92
Over 3.51.80price falling, opened at 1.87
Under 3.51.93price rising, opened at 1.87
Both teams to score
Yes1.67price rising, opened at 1.64
No2.08price falling, opened at 2.13
Odd/Even
Odd1.85price falling, opened at 1.86
Even1.85price rising, opened at 1.84
Handicap
Home -21.94
Away +21.78

What is the prediction for Toluca vs Santos Laguna?

Our correct score is 2-0, then 3-0. Both teams are in similar form heading into this match.

Methodology

Match analysis

Toluca have scored 14 goals and conceded just two across their last five Liga MX matches, a run that dwarfs anything Santos Laguna have managed away from home this month. Superior is backing that gap to hold with the home win in Toluca vs Santos Laguna on 21 September, priced at 1.30 with the model's confidence at 74 percent.

Toluca have scored 14 and conceded two in five matches

The run reads five straight wins: 1-0 away at Puebla, then home routs of Atlas (5-2), Monterrey (2-0), Leon (2-0) and FC Juarez (4-0). That puts Toluca's scoring average at 2.8 goals a game against Santos Laguna's 0.8, and the head to head backs the same story. Toluca have won the last three meetings between these two, 3-1, 4-2 away and 2-1, so recent history and current form point the same direction.

Santos Laguna's only win in five came on the road

Santos Laguna's five match log is one win, one draw and three losses, and that win was a 2-1 scoreline away at FC Juarez, the exact shape of result that would beat Toluca tonight. A draw needs Toluca to go scoreless for the first time in five games, and an away win needs Santos Laguna to repeat a performance they have not managed at home in three attempts this month.

Premium

After full time

Top five correct scores

  1. 2-011.6%Our score
  2. 3-011.4%Alternative
  3. 1-09.9%
  4. 2-19.1%
  5. 3-17.4%

Top five combined: 49.4%

Full score grid

Score Matrix

HomeTolucaxG2.47
AwaySantos LagunaxG0.74
0
1
2
3
4
5
6+
0
3.5%
9.9%
12%
11%
7.3%
3.7%
2.3%
1
2.5%
6.5%
9.1%
7.4%
4.8%
2.4%
1.5%
2
0.9%
2.3%
3.1%
2.8%
1.6%
0.8%
0.5%
3
0.3%
0.6%
0.8%
0.7%
0.4%
0.2%
0.1%
4
<0.1%
0.2%
0.2%
0.2%
<0.1%
<0.1%
<0.1%
5
<0.1%
<0.1%
<0.1%
<0.1%
<0.1%
<0.1%
<0.1%
6+
<0.1%
<0.1%
<0.1%
<0.1%
<0.1%
<0.1%
<0.1%

Goals and BTTS chances

Both teams to score Yes 46.4%53.6% No
Over 1.5 84.1%15.9% Under 1.5
Over 2.5 65.1%34.9% Under 2.5
Over 3.5 42.0%58.0% Under 3.5

Combos

Combos

Toluca win and over 2.5 goals56.5%
Toluca win and both teams score31.8%
Santos Laguna win and over 2.5 goals4.7%
Draw and under 2.5 goals10.0%
Outcome markets
Toluca or draw91.9%
Santos Laguna or draw21.9%
Either team wins86.1%
Draw no bet: Toluca90.6%
Draw no bet: Santos Laguna9.4%
Toluca win to nil46.3%
Santos Laguna win to nil3.8%
Team goals
Toluca to score92.7%
Santos Laguna to score50.2%
Toluca over 1.5 goals73.2%
Santos Laguna over 1.5 goals16.0%
Toluca clean sheet49.8%
Santos Laguna clean sheet7.3%

Today's acca

1 games, total odds 1.35

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Formations

Confirmed formations

Toluca: 4-2-3-1(confirmed lineup)Santos Laguna: 4-2-3-1(confirmed lineup)
Prediction, preview and head to head: Toluca vs Santos Laguna
Head to Head

Head to Head

Toluca vs Santos Laguna: Head-to-Head History
DateHomeScoreAway
15 January 2026Toluca3 - 1Santos Laguna
17 July 2025Santos Laguna2 - 4Toluca
7 April 2025Toluca2 - 1Santos Laguna
League Table

League Table

Liga MXMexico · 2026/2027
#TeamPWDLGFGAGDPtsForm
19612209+1119
29531178+918
38521178+917
4105231617-117
595041615+115
68422118+314
794231210+214
894231413+114
994231111014
1094141614+213
1193331510+512
1293331213-112
13102531215-311
1492341116-59
1592251016-68
169144913-47
179216915-67
189108623-173
Liga MX - League Table
PositionTeamPlayedWonDrawnLostGoals ForGoals AgainstGoal DifferencePointsForm
1Toluca96122091119WLW
2Guadalajara Chivas9531178918DWL
3Club America8521178917WDW
4Atlas105231617-117LWW
5Cruz Azul95041615115LWW
6Club Queretaro8422118314WWL
7Leon94231210214WLL
8Club Tijuana94231413114DWW
9Puebla94231111014DLW
10Monterrey94141614213WLW
11CF Pachuca93331510512LLW
12U.N.A.M. - Pumas93331213-112WWL
13Atlante FC102531215-311WDL
14Atletico San Luis92341116-59DDL
15Necaxa92251016-68LWW
16Tigres UANL9144913-47LDL
17Santos Laguna9216915-67LLL
18FC Juarez9108623-173LLL